A pharmaceutical isolator is a sealed, controlled system designed to provide a high level of protection for both the product and the operator during pharmaceutical manufacturing, compounding, research, or quality-control activities. Isolators create a physical barrier between the working environment and external surroundings to ensure sterility, containment, and safety.

Purpose of Pharmaceutical Isolators

Pharmaceutical isolators are used to:

• Maintain an aseptic environment for sterile drug preparation

• Protect operators from hazardous substances such as cytotoxic drugs

• Prevent contamination during compounding, filling, weighing, or testing

• Control environmental parameters such as airflow, humidity, and particulate levels

Key Types of Pharmaceutical Isolators

1. Aseptic Isolators

Used for sterile operations requiring contamination-free environments.Features include:

• HEPA-filtered unidirectional airflow

• Positive pressure to prevent external contamination

• Integrated glove ports for safe manipulation

Common uses: sterile filling, aseptic compounding, cell culture work.